Dawn

//

t My HBA1C reduced from 6.8 to 5.6 after more than 5 months Paleo diet. I have fasting sugar 140+ but through out the day whenever i measure (various random test) its always below 110.

Whats the reason for high FBS compared to other time ?

//

This is dawn effect

Nothing to worry

Since your random (except fasting) is below 110 and also since your HbA1c has also reduced, you need not worry

//At present i am taking 500mg glucophage at night//

Reduce the dose to 250 mg and you will see that your FBS comes down :) :) :)

//

Gokul Kumaran Go for very less carbohydrate that is less than 20 grams per day, have optimum protein not exceeding one gram per kg of your body weight per day. Have early dinner before 7 p.m. Practice some long fasting in the range of 36 to 44 hours in the week end.

//

Going for Low CHO is needed

I don't think other measures are needed

//

Gokul Kumaran This is because of gluconeogenesis that means making new glucose. Your liver is producing new glucose with the help of fat and protein at night.

//

Dawn effect is due to Gluconeogenesis, but that Gluconeogenesis is because of increased hyperglycaemic hormones as compared to insulin

So , restricting protein intake will NOT Help.

As I have explained many times,

Paleo is an unique state of Well Fed Ketosis in which metabolism differs from Fasting Ketosis

For Sudharsan Venkat, I suggest he reduces the Dose of his Night Hypoglycemic drug for one week and check again